Tumor Imaging Metrics Core
Co-Directors: Matthew Barish, Gordon Harris,
Annick Van den Abbeele
Locations: BWH, MGH, DFCI
| Core Summary: |
The Tumor Imaging Metrics Core provides and standardizes consistent and efficient radiological measurements such as linear dimension, tumor volume, total body burden, fuction, etc. to evaluate tumor response for DF/HCC clinical trials.
| Personnel/Contact Information: |
Co-Director (BWH): Matthew Barish, M.D.
Phone: (617) 732-6505
Fax: (617) 975-0946
Email: mbarish1@partners.org
Co-Director (MGH): Gordon Harris, Ph.D.
Phone: (617) 726-9464
Fax: (617) 724-6130
Email: gjharris@partners.org
Co-Director (DFCI): Annick Van den Abbeele, M.D.
Phone: (617) 632-2595
Fax: (617) 632-3581
Email: aabbeele@partners.org
Other Staff:
Core Manager: Bill Hanlon
Phone: (617) 643-0295
Fax: (617) 724-6130
Email: whanlon@partners.org
| Facilities and Equipment: |
Locations of Cores:
Brigham and Women's Hospital, 3D and Image Processing
Center
Massachusetts General Hospital, 3D Imaging Service
Dana-Farber Cancer Institute, Department of Radiology, Division of Nuclear
Medicine
Major Equipment:
Imaging network connecting five DF/HCC imaging centers
2D and 3D image analysis workstations
Image study archive (PACS)
| Services: |
The Tumor Metrics Core provides four primary services to DF/HCC investigators:
- Consultation services for image-based protocol and image analysis design
- Image aggregation and management of scans from all DF/HCC institutions
- Image measurement of lesions from scans of patients on clinical trials
- Results reporting and database management of radiological data for clinical trials
The Tumor Imaging Metrics Core will maintain a database
of longitudinal radiological and
clinical data that will link to the Quality Assurance for Clinical Trials (QACT)
Core to provide
an auditable record of quantitative measurements for clinical trials conducted
through the
DF/HCC.
| Fee Schedule/Rates: |
TIMC service fees (per scan) -- New rates apply to 09-xxx trials, effective 13-June-2008
| TIMC Service | DF/HCC
Member |
Non-DF/HCC
Member |
Industry-Sponsored |
| RECIST (1) ch/ab/pel (CT/MR) | $100 |
$200 |
$300 |
| WHO (2), IWRC (3), neuro, ch/ab/pel (CT/MR) | $100 |
$200 |
$300 |
| Cheson (4) (NHL) neck/ch/ab/pel (CT/MR) | $125 |
$250 |
$375 |
| SUV (5) neuro, maximum of five lesions (PET) | $125 |
$250 |
$375 |
| SUV whole body, maximum of five lesions (PET) | $125 |
$250 |
$375 |
| Choi (6) (CT w/contrast) | $150 |
$300 |
$450 |
| NCI-96 (CT/MR) | $150 |
$300 |
$450 |
| 3D Volume (7) - neuro, maximum of five lesions (MR) | $150 |
$300 |
$450 |
(1) RECIST - Response Evaluation Criteria for Solid Tumors
(linear).
(2) WHO - World Health Organization criteria (bi-directional).
(3) IWRC - International Workshop Response Criteria (bi-directional).
(4) Cheson (sum of products of perpendicular diameters). An additional charge
of one scan
time-point will be applied if measurements must be repeated from baseline;
i.e. if new target
lesions are identified for a subject in accordance with Cheson response criteria
guidelines.
(5) SUV - Standard Uptake Value, using body weight formula.
(6) Choi - RECIST plus density measurements on CT scans w/contrast.
(7) Includes modified RECIST measurements for brain.
| Getting Started: |
To access the core, please contact Bill Hanlon at (617)
632-6578 or by email at
whanlon@partners.org. Core services can also be requested by selecting
TIMC services
on the DFCI IRB New Project Request Form.
| Departmental Web Link: |
http://www.dfhcc.harvard.edu/core-facilities/tumor-imaging-metrics/
