MGH RESEARCH CORES

Morphometry Analysis
CCIB DNA Core
Clinical Genetic Research Facility
Clinical Research Program
Drosophila Genetics Core
Flow Cytometry Core
Flow Cytometry Core (Ragon Institute)
Glass Washing and Autoclaving Core
Martinos Center- Technology Core
Microscopy Core (Brown)
Microscopy Core (Ragon Institute)
Morphometric Analysis Center
Musculoskeletal Imaging Research Core
Neuroscience Microscope Core
PET Core
Radiation Safety Core
Recombinant Protein Expression and Purification Core
Research Computing Core
Research Informatics Core
Transgenic and Gene Targeting Facility
Tumor Imaging Metrics Core
Vector Development and Production Core
 

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MGH Morphometric Analysis Center
Director: Nikos Makris
Location: Building 149 13th Street, Room 10.006, Charlestown

 

Core Summary:

The MGH Morphometric Analysis Center (MMAC) is established for the generation of neuroanatomic morphometric measurements. The operational synergies in the combined approaches of the Center for Morphometric Analysis (CMA) and the Martinos Center for Biomedical Imaging as well as the commonality of the application areas represent a unified approach to the delivery of these morphometric measures to the Partners community. The Core transitions morphometric methods developments into ‘production mode’, as the efficiency and quantity of application areas grow. The MGH Morphometric Analysis Center provides the infrastructure to support the necessary level of administrative, operational, financial and physical presence that is necessary to provide a more efficient, cost effective and flexible morphometric measurement service to meet the needs of the clinical community.

Personnel/Contact Information:

Director: Nikos Makris, M.D., Ph.D.
Phone: (617) 726-5743
Fax: (617) 726-5711
Email: nikos@cma.mgh.harvard.edu

Other Staff:

Bruce Fischl, Ph.D.
Email:
fischl@nmr.mgh.harvard.edu

Brad Dickerson, M.D.
Email: bradd@nmr.mgh.harvard.edu

Facilities and Equipment:

Location of Core:

The facility is located at Building 149 13th Street, Room 10.006, Charlestown.

Major Equipment:
  • (16) Dual Pentium processors running Linux. 1024+Mby RAM.
  • 2+ TB online RAID disk space for storing images and morphometric data and for developing software.
  • (4) Linix-based servers; 1 dedicated web services, 1 dedicated to CD writing for permanent data backup and storage and 2 dedicated file servers each serving a RAID disk systems.
Services:

The services that are offered fall into two classes of anatomic procedure: ‘General Segmentation’ and ‘Cortical Parcellation’. General Segmentation includes all principle gross structures of the human brain, including cortex, white matter, and cerebral deep gray matter structures. Cortical Parcellation involves assessment of the cerebral cortex in the context of gyral-based regions.

Each of the classes of anatomic analysis can be delivered in an ‘automated’ and ‘manual’ mode. The ‘manual’ mode involves substantial technician involvement in all stages of the segmentation procedures, and follows a long established analysis and anatomic definition protocol. The ‘automated’ mode involves reduced technician intervention, but follows newer, computationally encoded anatomic analysis conventions.

FY12 User Fees (Effective 10/1/11-9/30/12):

Service
Internal Users
External Users
Class of Anatomic Structure
Automatic/Manual
Partners
Non Partners AMC & Non-Profit
For-Profit & Industry
General Segmentation Semi-Automated
$780
$1,120.00
$1,234.33
Cortical Parcellation Semi-Automated
$520
$750.00
$822.92
Engineering Consulting Service Automated
$50
$72.00
$79.20

 

Getting Started:

To access the core, please contact Nikos Makris by email at nikos@cma.mgh.harvard.edu.

Departmental Web Link:

http://www.nmr.mgh.harvard.edu/

http://www.cma.mgh.harvard.edu/