MGH RESEARCH CORES

Morphometry Analysis
Biostatistics Core
Clinical Genetic Research Facility
Clinical Research Program
DNA Microarray Core (Seed)
DNA Sequencing Core
DNA Synthesis Core
Electrophysiology Core
Flow Cytometry Core
Glass Washing and Autoclaving Core
Knight Surgical Research Laboratory
Knockout Facility
Laser Capture Microscopy Core
Magnetic Resonance Imaging Core
Microscopy and Image Analysis Core
Microscopy Core (Brown)
Model Shop (Prototyping and Fabrication Facility)
Morphometry Analysis Center
Musculoskeletal Imaging Research Core
Neuroscience Microscope Core
Nucleic Acid Quantitation (Real-Time PCR) Core
Peptide Synthesis/Protein Sequencing Core
PET Core
Radiation Safety Core
Transgenic Core
Transgenic Drosophila Fly Core
Tumor Imaging Metrics Core
Vector Development and Production Core
Web Development Core
 

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Morphometry Analysis Center
Director: David Kennedy
Location: Building 149 13th Street, Room 6014, Charlestown

 

Core Summary:

The MGH Morphometric Analysis Center (MMAC) is established for the generation of neuroanatomic morphometric measurements. The operational synergies in the combined approaches of the Center for Morphometric Analysis (CMA) and the Martinos Center for Biomedical Imaging as well as the commonality of the application areas represent a unified approach to the delivery of these morphometric measures to the Partners community. The Core transitions morphometric methods developments into ‘production mode’, as the efficiency and quantity of application areas grow. The MGH Morphometric Analysis Center provides the infrastructure to support the necessary level of administrative, operational, financial and physical presence that is necessary to provide a more efficient, cost effective and flexible morphometric measurement service to meet the needs of the clinical community.

Personnel/Contact Information:

Director: David Kennedy, Ph.D.
Phone: (617) 726-5621
Fax: (617) 726-5711
Email: dave@cma.mgh.harvard.edu

Other Staff:

Co-Director: Nikos Makris, M.D., Ph.D.
Phone: (617) 726-5733
Fax: (617) 726-5711
Email: nikos@cma.mgh.harvard.edu

Bruce Fischl, Ph.D.
Email:
fischl@nmr.mgh.harvard.edu

Brad Dickerson, M.D.
Email: bradd@nmr.mgh.harvard.edu

Facilities and Equipment:

Location of Core:

The facility is located at Building 149 13th Street, Room 6014, Charlestown.

Major Equipment:

(16) Dual Pentium processors running Linux. 1024+Mby RAM.
2+ TB online RAID disk space for storing images and morphometric data and for developing software.
(4) Linix-based servers; 1 dedicated web services, 1 dedicated to CD writing for permanent data backup and storage and 2 dedicated file servers each serving a RAID disk systems.

Services:

The services that are offered fall into two classes of anatomic procedure: ‘General Segmentation’ and ‘Cortical Parcellation’. General Segmentation includes all principle gross structures of the human brain, including cortex, white matter, and cerebral deep gray matter structures. Cortical Parcellation involves assessment of the cerebral cortex in the context of gyral-based regions.

Each of the classes of anatomic analysis can be delivered in an ‘automated’ and ‘manual’ mode. The ‘manual’ mode involves substantial technician involvement in all stages of the segmentation procedures, and follows a long established analysis and anatomic definition protocol. The ‘automated’ mode involves reduced technician intervention, but follows newer, computationally encoded anatomic analysis conventions.

Fee Schedule/Rates:

Service
MGH
Non-MGH
General Segmentation, Manual
$1,000
$1,600
General Segmentation, Automated
$625
$1,000
Cortical Parcellation, Manual
$600
$960
Cortical Parcellation, Automated
$225
$360

Getting Started:

To access the core, please contact David Kennedy by email at dave@cma.mgh.harvard.edu.

Departmental Web Link:

http://www.nmr.mgh.harvard.edu/

http://www.cma.mgh.harvard.edu/

http://dem0nmac.mgh.harvard.edu/