MGH RESEARCH CORES

Clinical Research Program
Biostatistics Core
Clinical Genetic Research Facility
Clinical Research Program
DNA Microarray Core (Seed)
DNA Sequencing Core
DNA Synthesis Core
Electrophysiology Core
Flow Cytometry Core
Glass Washing and Autoclaving Core
Knight Surgical Research Laboratory
Knockout Facility
Laser Capture Microscopy Core
Magnetic Resonance Imaging Core
Microscopy and Image Analysis Core
Microscopy Core (Brown)
Model Shop (Prototyping and Fabrication Facility)
Morphometry Analysis Center
Musculoskeletal Imaging Research Core
Neuroscience Microscope Core
Nucleic Acid Quantitation (Real-Time PCR) Core
Peptide Synthesis/Protein Sequencing Core
PET Core
Radiation Safety Core
Transgenic Core
Tumor Imaging Metrics Core
Vector Development and Production Core
Web Development Core
 

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Clinical Research Program
Director: William Crowley
Location: 185 Cambridge Street, Simches 2153, Boston
 

Core Summary:

The Clinical Research Program (CRP) is the MGH’s infrastructure for clinical investigators. Through five units, it provides direct services to faculty and staff for all types of clinical research (translational, trials and outcomes). The CRP also develops innovative tools to anticipate and enable future research opportunities.

Personnel/Contact Information:

Director: William Crowley, M.D.
Phone: (617) 726-5390
Fax: (617) 726-5357
Email: wcrowley@partners.org

Other Staff:

Admin/Finance: Constance Stubbs
Phone: (617) 726-5520
Fax: (617) 726-5501
Email: cstubbs@partners.org

Operations: Kay Ryan
Phone: (617) 726-3608
Fax: (617) 726-5501
Email: kryan10@partners.org

Clinical Research Education Unit:

Director: Eric Rosenberg, M.D.
Phone: (617) 724-7519
Fax: (617) 726-3795
Email: erosenberg1@partners.org

Clinical Research Support Office:

Director: G. Scott Gazelle, M.D., Ph.D., M.P.H.
Phone: (617) 726-4047
Fax: (617) 726-9414
Email: scott@mgh-ita.org

Genetics & Genomics Unit:

Co-Director: Jordan Smoller, M.D., Sc.D.
Phone: (617) 724-0835
Fax: (617) 643-3080
Email: jordan_smoller@hms.harvard.edu

Co-Director: Susan Slaugenhaupt, Ph.D.
Phone: (617) 643-3091
Email: slaugenhaupt@chgr.mgh.harvard.edu

Disease Management Unit:

Co-Director: James Meigs, M.D., M.P.H.
Phone: (617) 724-3203
Fax: (617) 724-3544
Email: jmeigs@partners.org

Co-Director: Richard Grant, M.D., M.P.H.
Phone: (617) 724-3502
Email: rgrant@partners.org

Information Unit:

Director: Henry Chueh, M.D., M.S.
Phone: (617) 724-7985
Fax: (617) 726-8481
Email: chueh.henry@mgh.harvard.edu

Facilities and Equipment:

Location of Core:

185 Cambridge Street, Simches Building CPZN 2153, Boston.

Major Equipment:

CHGR’s Phenotyping Core is available for study visits.

Services:
  • Education Unit - offers courses and seminars that address the unique and rapidly changing needs of clinical investigators and study staff. The curriculum targets young faculty who need to learn the methods of clinical investigation as well as more experienced investigators needing to fill gaps in knowledge. The Unit also supports an active program of orientation and continuing education in regulation and operations for coordinators and research nurses. Courses include biostatistics, genetics, trial design & conduct, human protection, grant writing, scientific writing, recruitment, etc.
  • Clinical Research Support Office (CRSO) – provides services to assist investigators with study design, biostatistical consultation, funding sources, budgets, IRB submissions, recruitment, and study coordination. Also provides resources for investigators’ career development (e.g., mentorship and the “K Society”) and advocates for clinical investigators within the MGH system.
  • Genetics and Genomics Unit – provides consultation, educational programs and resource referral to assist investigators with incorporation of genetics and genomics into protocols. Works to link investigators with resources in other genetics programs including MGH’s Center for Human Genetic Research, Harvard Partners Center for Genetics and Genomics, and the Broad Institute.
  • Disease Management and Outcomes Unit - supports hypothesis-driven research that improves patient outcomes through systemic changes in system, provider and patient behaviors while fostering careers of junior faculty. Working with “Clinical Champions” on selected common diagnoses, the Unit helps develop important clinical research questions, identifies patterns of care and individual variation, and supplies computer applications that link clinical data, care guidelines and data for research.
  • Information Management Unit – Based in the Lab of Computer Science, the Unit creates significant and novel information management infrastructure to support and amplify clinical research. It establishes partnerships with investigators to implement pilot studies with clinical informatics-based interventions, creating reusable technology platforms. It also supports the recruitment, communication and educational requirements of the CRP. For example, in response to investigators’ needs to identify potential subjects and find relevant information via ‘one stop shopping’ it b uilt the Research Patient Data Registry (RPDR). It also created tools for the Research Subject Volunteer Program (RSVP), a registry of people interested in participating studies.
Fee Schedule/Rates:

Service
MGH
All services are free except:
IRB submission
$1,800
IRB submission for pediatric studies
$2,200
Study coordination
$39/hour
Database consultation and management
$80/hour
Select educational offerings
As noted

Getting Started:

To access the core, please contact the Unit Directors identified above or Kay Ryan at
(617) 726-3608 or by email at
kryan10@partners.org.

Departmental/Other Web Link:

www.massgeneral.org/crp/

www.ahcforum.org/