MGH RESEARCH CORES

DNA Synthesis
Biostatistics Core
Clinical Genetic Research Facility
Clinical Research Program
DNA Microarray Core (Seed)
DNA Sequencing Core
DNA Synthesis Core
Electrophysiology Core
Flow Cytometry Core
Glass Washing and Autoclaving Core
Knight Surgical Research Laboratory
Knockout Facility
Laser Capture Microscopy Core
Magnetic Resonance Imaging Core
Microscopy and Image Analysis Core
Microscopy Core (Brown)
Model Shop (Prototyping and Fabrication Facility)
Morphometry Analysis Center
Musculoskeletal Imaging Research Core
Neuroscience Microscope Core
Nucleic Acid Quantitation (Real-Time PCR) Core
Peptide Synthesis/Protein Sequencing Core
PET Core
Radiation Safety Core
Transgenic Core
Tumor Imaging Metrics Core
Vector Development and Production Core
Web Development Core
 

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DNA Synthesis Core
Director: Andrew Moeller
Location: 38 Sidney Street, Cambridge
 

Core Summary:

The DNA Synthesis Core offers multiple scale synthesis of DNA oligonucleotides, both modified and unmodified.

Personnel/Contact Information:

Director: Andrew Moeller
Phone: (617) 726-7901
Fax: (617) 726-0077
Email: amoeller@ccib.mgh.harvard.edu

Facilities and Equipment:

Location of Core:

The facility is located at 38 Sidney Street, Suite 100, Cambridge.

Major Equipment:

ABI Expedite 8900 Nucleic Acid Synthesizer
BioAutomation Mermade V
Combisep

Services:

Synthesis of DNA oligonucleotides at the 50 nm, 200nm and 1.0um scales.
Modifications and phosphorothioate linkages are also available.
Oligos can be desalted and/or QC’d with capillary electrophoresis

Fee Schedule/Rates:

Service
MGH
50 nanomole synthesis
$0.22/base
200 nanomole synthesis
$0.50/base
1.0 micromole synthesis
$1.00/base
High Throughput 50 nanomole (96 oligos or more)
$0.18/base
Desalting
$1.00
Capillary Electrophoresis
$100/96-well plate

Getting Started:

To register or order oligos you should go to:

https://dnacore.mgh.harvard.edu/cgi-bin/login

Once you have registered and created a user account, you will be able to place your oligo
orders over the web.

To access the core, please contact Andy Moeller at (617) 726-7901 or by email at
amoeller@ccib.mgh.harvard.edu.

Departmental Web Link:

https://dnacore.mgh.harvard.edu/synthesis/index.shtml