Director: Sabina Signoretti
Location: 20 Shattuck Street, Thorn 630, Boston
| Core Summary: |
The Tissue Microarray (TMA) Core generates tissue microarrays
that allow hundreds of
tumors and samples to be evaluated on a single slide, maximizing precious tissue
resources.
The Core also provides access to TMA Profiler, a Web-based database that facilitates
data
dissemination and sharing.
| Personnel/Contact Information: |
Director: Sabina Signoretti, M.D.
Phone: (617) 525-7437
Fax: (617) 264-5169
Email: ssignoretti@partners.org
Other Staff:
Associate Pathologist: Scott Rodig, M.D., Ph.D.
Research Assistant, TMA Construction: Chungdak Namgyal
Research Assistant, Nucleic Acid Isolation: Yu Yang
Core Administrative Coordinator: Lauri Wyner
Phone: (617) 432-4947
Fax: (617) 432-6474
Email: lauri_wyner@hms.harvard.edu
| Facilities and Equipment: |
Location of Core:
The facility is located at 20 Shattuck Street, Thorn 630, Boston.
| Services: |
►Construction
of standard and custom TMAs
►Preparation
of slides
►Image acquisition
and analysis
►Access
to and training on the TMA Profiler
►Consultation
| FY12 User Fees (Effective 10/1/11): |
| Service | Internal Users |
External Users |
|||
Partners DF/HCC Member* |
Partners Non-DF/HCC Member |
Academic/Non-Profit - DF/HCC Member |
Academic/Non-Profit - Non-DF/HCC Member |
For-Profit & Industry |
|
| Additional TMA Slide Acquisition & Storage from Previously Digitized TMA for Aperio (Array Slide) | $26.79 |
$43.91 |
$26.79 |
$63.23 |
$87.27 |
| Aperio Image Analysis Tools for Standard Slide (Slide) | $18.84 |
$30.89 |
$18.84 |
$44.49 |
$61.40 |
| Aperio Image Analysis Tools for TMA Slide (Array Slide) | $526.56 |
$863.21 |
$526.56 |
$1,243.03 |
$1,715.63 |
| TMA Block Setup | $38.81 |
$63.63 |
$38.81 |
$91.62 |
$126.46 |
| Core Punch Charge for TMA construction (Core) | $3.62 |
$5.94 |
3.62 |
$8.55 |
$11.80 |
| Core Punch Only for DNA (no construction or isolation) (Core) | $0.96 |
$1.57 |
$0.96 |
$2.25 |
$3.11 |
| Core Punch Only for RNA (no construction or isolation) (Core) | $1.27 |
$2.09 |
$1.27 |
$3.00 |
$4.15 |
| DNA Isolation (Well) | $7.93 |
$13.00 |
$7.93 |
$21.29 |
$25.84 |
| H&E Staining (Array Slide) | $37.53 |
$61.53 |
$37.53 |
$88.61 |
$122.30 |
| Picogreen Estimation of DNA Yield (Core) | $1.83 |
$3.00 |
$1.83 |
$4.32 |
$5.96 |
| Ribogreen Estimation of DNA Yield (Core) | $1.83 |
$3.00 |
$1.83 |
$4.32 |
$5.96 |
| RNA Isolation (Well) | $8.54 |
$14.00 |
$8.54 |
$20.16 |
$27.83 |
| Standard Sectioning – Array Block (Array Slide) | $3.24 |
$5.32 |
$3.24 |
$7.65 |
$10.57 |
| Standard Slide Acquisition & Storage for Aperio (Slide) | $9.76 |
$16 |
$9.76 |
$23.04 |
$31.80 |
| Technical Assistance/Consultation | $51.37 |
$84.22 |
$51.37 |
$121.27 |
$167.38 |
| TMA Pathologist Consultation (Hour) | $96.63 |
$158.42 |
$96.63 |
$228.12 |
$314.85 |
| TMA Slide Acquisition & Storage for Aperio (Array Slide) | $976.56 |
$1,600.92 |
$976.56 |
$2,305.33 |
$3,181.84 |
| AQUA Unassisted (Hour) | $53.09 |
$87.03 |
$53.09 |
$125.33 |
$172.98 |
| Punch File Creation (Hour) | $38.41 |
$62.97 |
$38.41 |
$90.68 |
$125.16 |
| Getting Started: |
To access the core, please contact Sabina Signoretti
at (617) 525-7437 or by email at
ssignoretti@partners.org.
| Departmental Web Link : |
http://www.dfhcc.harvard.edu/core-facilities/tissue-microarray-and-imaging-pathology/
